Common solvents

  • CDCl3 -- This solvent has good purity, dissolve many compounds and is the primary solvent used.
  • Acetone-d6 -- A great solvent, not too expensive, although not as polar as others.
  • CD2Cl2 -- This solvent is excellent. Ideal for low temperature chemistry.
  • Toluene-d8 -- Very good for low and high temperature work
  • CD3CN -- This is usually a good choice when a more polar solvent is needed.
  • DMSO-d6 -- This is usually a poor choice although it is not expensive.
  • THF-d8 -- This solvent is expensive.

Ref: https://web.nmsu.edu/~kburke/Instrumentation/NMR_Solv.html